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A 32-month old boy with autism spectrum disorder showed significant improvement in behavioral problems after treatment with vitamin D3 (cholecaliferol), according to a study published Dec. 15 in Pediatrics, the journal of the American Academy of Pediatrics.

“To our knowledge, this is the first case report of a case with ASD and vitamin D deficiency whose autism symptoms markedly improve after vitamin D supplementation,” the authors, led by Feiyong Jia, PhD, MD, wrote in the study. “Vitamin D deficiency is a common nutritional disorder, and one of the most common undiagnosed medical conditions in the world. Recent studies suggested that vitamin D deficiency is a common phenomenon in children with ASD, and vitamin D deficiency may be involved in the process of autoantibody production in patients with autism.”

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